Explosions were heard in Tehran early Wednesday as Israeli warplanes pounded Iran’s capital overnight and into Wednesday. Iran’s supreme leader on Wednesday rejected U.S. calls for surrender and warned that any military involvement by the Americans would cause “irreparable damage” to them.

Explosions were heard in Tehran early Wednesday as intense Israeli airstrikes again targeted Iran’s capital in a conflict that a human rights group said had killed at least 585 people across Iran and wounded 1,

Israel and Iran have attacked each other for a fifth straight day on Tuesday with President Donald Trump urging Iranians to evacuate Tehran. Since the Israeli strikes on Friday, the two Middle Eastern rivals have exchanged blows, with Iranian officials reporting more than 220 deaths, mostly civilians, while Israel said 24 civilians had been killed.