If the U.S. entered the conflict between Iran and Israel, Tehran could target American military assets in the region, experts have told Newsweek.

The Israeli military said Iran launched retaliatory strikes throughout the night. This followed a major Israeli attack on Friday, targeting Iran's nuclear facilities and killing top military leaders.

Iran's Ministry of Defense has vowed to continue retaliatory strikes against Israel, declaring its intent to "break the back" of the Zionist regime. In a live interview with Press TV, ministry spokesperson Brigadier General Reza Talaei-Nik said Iran's armed forces will deliver "devastating blows" to Israel in response to recent aggression.

Iran's Supreme Leader Ayatollah Ali Khamenei said Israel “should expect severe punishment” for the attacks, which he said struck residential centers and killed several commanders and scientists. “The powerful hand of the armed forces of the Islamic Republic will not let them go unpunished,

Although Iran maintains that its nuclear program is for peaceful energy purposes, Israel has long seen it as a threat. Israeli strikes have hit three of Iran’s nuclear facilities — Natanz, Isfahan and Fordow. Little damage appears visible in satellite imagery of Fordow.

Iran missile exchange, a startling claim by a senior Iranian general has put Pakistan in an uncomfortable spotlight. While Tehran insists that Islamabad has pledged nuclear retaliation against Israel,

Sirens sounded in Israel as Iran launched dozens of ballistic missiles in retaliation for Israel's strikes on its nuclear facilities.

According to Human Rights Activists, a Washington-based monitoring group, at least 406 people in Iran have been killed in the ongoing strikes, with over 650 more injured. Iran’s government has yet to release official casualty figures.